What is the best way for me to clean a vintage clutch purse with simulated pearls and sequins?

I found this amazing vintage clutch purse at a yard sale. It is in very good shape, but very dirty. The pearls look tan instead of white! I rubbed it gently and some of the dirt came off right away, so it appears to be surface dirt rather than the pearls and sequins turning color. Would it be ok to clean it with a soft, damp toothbrush? If not, what is the best way to clean it?